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The Infected (occasionally referred to as Boils) are ex-Hyperion workers who have fallen victim to an affliction known as Space Hurps that infects the Veins of Helios. The Infected have since degenerated into a group of psychotic cannibals roaming the Veins of Helios in search of human flesh to consume. All Infected wear remnants of their old Hyperion uniforms and feature enormous boils infesting their skin.
- Killing Infected contributes to the 'Dose of Death' challenge.
- Infected share many traits to the rats of Pandora, including their hunched, sneaky style of movement.
- The only type of Infected that does not initially wear a helmet to keep its facial boils under control are Badass Boils.
- Infected are hostile to Lost Legion troops, and will engage them if their attention isn't focused on a Vault Hunter.
- When Vault Hunters are under the full effects of Space Hurps during the mission Trouble with Space Hurps, Infected will have alternate names (see the mission page for a listing). However, if a Vault Hunter is under the full effect of Space Hurps after the mission is complete, the alternate names will not return.