- Showdown
- Showdown (Nisha)
- Showdown (mission)
- Showdown (mission)/Transcript
- Shredda
- Shredder
- Shredder Fanatic
- Shredifier
- Shredifier/Variant Chart
- Shredifier (Borderlands 3)
- Shredifier (Borderlands 3)/Variant Chart
- Shrieking Devil
- Shrike
- Shrine
- Shrine Pieces
- Shroomlet
- Shroomoner
- Shrooms
- Shuggurath (enemy)
- Shuggurath (species)
- Shuggurath of Ice
- Sic 'Em
- Sickener Krich
- Sickle
- Sickle (assault rifle)
- Sickle (assault rifle)/Variant Chart
- Side Pisces
- Sidewinder
- Siege of Castle Crimson
- Sigil
- Sigmand
- Signal to Noise
- Signal to Noise/Benediction of Pain
- Signal to Noise/Castle Crimson
- Signal to Noise/Sapphire's Run
- Sigrdrifa
- Silence the Voices
- Silent Night
- Silent Resolve
- Silicone Ring
- Silvan
- Silver
- Silver Lining
- Simon
- Singing Psycho
- Singlejack (AR)
- Singularity Grenade
- Singularity Grenade/Variant Chart
- Sinister Sounds
- Sinkhole
- Sir Boil
- Sir Gallow
- Sir Hammerlock
- Sir Hammerlock's Big Game Hunt
- Sir Hammerlock's Big Game Hunt mission flow
- Sir Hammerlock/Quotes
- Sir Hammerlock vs. the Son of Crawmerax
- Sir Mash
- Sir Reginald
- Sir Stew
- Siren
- Siren's Song
- Sirentology
- Sirentology/Transcript
- Sisterly Love
- Six-Shooter
- Six Galaxies
- Skag
- Skag-Trap
- Skag/Gallery
- Skag Dog Days
- Skag Dog Days/Transcript
- Skag Gully
- Skag Gully: Weapon Crate Locations
- Skag Pup
- Skag Rapparee
- Skag Ravager
- Skag Rider
- Skag Rustler
- Skag Whelp
- Skag of Survival
- Skags At The Gate
- Skagzilla
- Skagzilla (technical)
- Skatergun
- Skatergun/Variant Chart
- Skeep
- Skeep Prod
- SkekSil
- SkekSil/Variant Chart
- Skelecrab
- Skelerakk
- Skeleton
- Skeleton (TTWL)
- Skeleton (enemy)
- Skeleton (faction)
- Skeleton Archer
- Skeleton Army
- Skeleton Cultist
- Skeleton Fuselighter
- Skeleton King
- Skeleton Seer
- Skeleton Swordsman
- Skiffless
- Skill
- Skin of the Ancients
- Skin of the Ancients/Variant Chart
- Skin to Win (Ashfall Peaks)
- Skin to Win (Bloodsun Canyon)
- Skin to Win (Obsidian Forest)
- Skin to Win (The Blastplains)
- Skittermaw Basin
- Skrakk
- Skrakk (Borderlands 3)
- Skrappy
- Skrappy "all grown up"
- Skrit
- Skuldugger
- Skullantir
- Skullmasher
- Skullmasher (Borderlands)
- Skullmasher (Borderlands: The Pre-Sequel)
- Skullmasher (Borderlands: The Pre-Sequel)/Variant Chart
- Skullmasher (Borderlands 2)
- Skullmasher (Borderlands 2)/Variant Chart
- Skullmasher (Borderlands 3)
- Skullmasher (Borderlands 3)/Variant Chart
- Sky Bullies
- Skyman
- Skyscraper
- Skywell-27
- Slab
- Slab (class mod)
- Slab UHF
- Slabs
- Slag
- Slagga
- Slagga/Variant Chart
- Slagged Psycho
- Slagged Rakk
- Slagged Scaylion
- Slagged Spiderant
- Slagged Stalker
- Slagged Thresher
- Slagy
- Slagy/Variant Chart
- Slammer
- Slammer/Variant Chart
- Slammin' Salmon
- Slap-Happy
- Slap-Happy/Transcript
- Slapper
- Slapper/Variant Chart
- Slasher Grawn
- Slaughterhouse Psycho
- Slaughterstar 3000
- Slaughterstar 3000 (mission)
- Slayer
- Slayer Of Terramorphous
- Sledge
- Sledge's Safe House
- Sledge's Safe House: Weapon Crate Locations
- Sledge's Shotgun
- Sledge's Shotgun (Borderlands)
- Sledge's Shotgun (Borderlands 2)
- Sledge's Shotgun (Borderlands 2)/Variant Chart
- Sledge's Shotgun (Borderlands 3)
- Sledge's Shotgun (Borderlands 3)/Variant Chart
- Sledge's Shotty
- Sledge's Shotty/Variant Chart
- Sledge: Battle For The Badlands
- Sledge: Meet Shep
- Sledge: The Mine Key
- Sledge: To The Safe House
- Sleeping Giant
- Sleeping Giant/Variant Chart
- Slick Delivery
- Slider
- Slim
- Slinger
- Slip 'n' Stun
- Slither
- Slithermaw
- Slorgok the Fecund
- Slot Machine
- Sloth
- Sloth/Variant Chart
- Sloth (enemy)
- Slow Hand
- Slow Hand/Variant Chart
- Slow Hand (Borderlands 3)
- Slugger
- Sly Trivern
- Small Tournament
- Smaller, Lighter, Faster
- Smaller-than-average Timothy
- Smart-Gun
- Smart-Gun/Variant Chart
- Smart Armor
- Smash-Head
- Smashammer
- Smasher
- Smasher/Variant Chart
- Smasher (disambiguation)
- Smashin' Pumpkins
- Smells Like Victory
- Smells Like Victory/Transcript
- Smig
- Smig/Variant Chart
- Smirk
- Smite
- Smithy's Ire
- Smog
- Smoke Signals: Investigate Old Haven
- Smoke Signals: Shut Them Down
- Snake Stick
- Snap Shot
- Snapper
- Sneaky Little Buggers
- Snider
- Snider/Variant Chart
- Sniper
- Sniper.Runtime
- Sniper (Borderlands 2)
- Sniper (Borderlands 2)/Variant Chart
- Sniper (Title)
- Sniper (class mod)
- Sniper (skill tree)
- Sniper Rifle
- Sniper Rifle/parts
- Sniper Rifle (Hyperion legacy)
- Sniper Rifle (Hyperion legacy)/Variant Chart
- Sniper Rifle (Title)
- Sniper Rifle (Title)/Variant Chart
- Sniper Rifle Parts (BL3 Dahl)
- Sniper Rifle Parts (BL3 Hyperion)
- Sniper Rifle Parts (BL3 Jakobs)
- Sniper Rifle Parts (BL3 Maliwan)
- Sniper Rifle Parts (BL3 Vladof)
- Sniper Rifle Parts (Borderlands 2/TPS)
- Sniping
- Snoring Valley
- Snow Skag
- Snowball
- Snowball/Variant Chart
- Snowdrift
- Snowflake
- Snowflake/Variant Chart
- So Much Blood!
- Soapy Steve
- Soldier Sergeant
- Soleki Protocol
- Soliloguy Scientific
- Solitaire
- Some for the Road
- Son of Flamey
- Son of Mothrakk
- Sorcerer
- Sorcerer's Daughter
- Soul Purpose (mission)
- Soul Sap
- Soulfire
- Soulrender
- Soundtrack
- Southern Raceway
- Southern Shelf
- Southern Shelf - Bay
- Southpaw Steam & Power
- Spa Vs. Spa
- Space-Laser Tag
- Space Cowboy
- Space Cowboy/Transcript
- Space Hurps
- Space Slam
- Space Slam/Transcript
- Spade
- Spark
- Spark (Lilith)
- Spark (SMG)
- Spark (SMG)/Variant Chart
- Spark Plug
- Sparky Flynt
- Sparrow
- Spatula Khan
- Spawnling Shroom
- Special
- Special/Variant Chart
- Special Delivery
- Special Weapon Effects
- Special Weapon Effects (Borderlands: The Pre-Sequel)
- Special Weapon Effects (Borderlands 2)
- Specialist
- Specialist Bear
- Specter Malech
- Spectral Aegis
- Spectral Shuggurath
- Spectral Talons
- Spectral Trampler
- Spectre
- Speed Kills
- Speedy McSpeederton
- Spell Books
- Spell Sniper
- Spell to Pay
- Spellblade
- Spellshot
- Spellshot/Skill tree
- Spiced Gingerdead
- Spicy
- Spicy/Variant Chart
- Spider
- Spiderant
- Spiderant-Trap
- Spiderant (Borderlands 3)
- Spiderant Bishop
- Spiderant Centurion
- Spiderant Countess
- Spiderant Gyro
- Spiderant King
- Spiderant Knight
- Spiderant Queen
- Spiderant Rook
- Spiderant Scorcher
- Spiderant Sentinel
- Spiderant Soldier
- Spiderant Warrior
- Spiderant Worker
- Spiderantling
- Spiderling
- Spiderpants
- Spike Shield
- Spike Shield/Variant Chart
- Spikehound
- Spiker
- Spiker/Variant Chart
- Spinigun
- Spinigun/Variant Chart
- Spire
- Spirit Rune
- Spiritual Driver
- Spiteful Bloom
- Spitter
- Spitter/Variant Chart
- Spitter Skag
- Splainer
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