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Suicide Spiders are enemies encountered in the DLC Tiny Tina's Assault on Dragon Keep. They are orange in color and have a prominent abdomen.
Suicide Spiders only form of attack is to rush to a target and blow themselves up. The explosion generated by their death is powerful, but not extremely so. Still, they should be taken out before they have a chance to get close. Unlike their brethren, they are resistant to incendiary damage. A Suicide Spider's critical hit location is its abdomen, and this presents quite a large target to shoot at.
- When a Suicide Spider dies, the explosion it creates damages friend and foe alike. Therefore it is beneficial to kill them when they are in the midst of their allies.
- In True Vault Hunter Mode, Suicide Spiders become "Unstable Spiders."